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Generic Nicoumalone uses: Nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the UK), which is a type of medicine called an oral anticoagulant. It is used to stop blood clots forming within the blood vessels. Blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. The clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood. Clotting factors are proteins that are produced by the liver. Vitamin K is essential for their production. The activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. Fibrin binds the platelets together, forming a blood clot. This is the body's natural way of repairing itself. Sometimes, however, a blood clot can form abnormally within the blood vessels. This is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. The clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. This is known as a thromboembolism.Some people have an increased tendency for blood clots to form within the blood vessels. This is usually due to a disturbance in the blood flow within the blood vessels. For example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. Slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). These clots can break off and travel to the lungs (pulmonary embolism). A type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. Heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. Clots in the heart can detach and travel to the brain, causing a stroke. Acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. Acenocoumarol works by preventing the vitamin K dependent production of the clotting factors described above. Acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin K. Without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur.Acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up. For this reason, when treating blood clots such as deep vein thrombosis (DVT) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with.The anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added. This time is expressed as the International Normalised Ratio (INR). Your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your INR fall into the range that has been shown to be effective at preventing blood clots in your particular condition.What is it used for?Treating and preventing blood clots in the blood vessels, for example in the following cases:Preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves Treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) Treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism)

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sometimes, however, a blood clot can form abnormally within the blood vessels. your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition. acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above. this is the body's natural way of repairing itself. this is usually due to a disturbance in the blood flow within the blood vessels. the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood. acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k. a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant. fibrin binds the platelets together, forming a blood clot.some people have an increased tendency for blood clots to form within the blood vessels.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added. vitamin k is essential for their production. for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with. for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. this is known as a thromboembolism. clotting factors are proteins that are produced by the liver. clots in the heart can detach and travel to the brain, causing a stroke. this time is expressed as the international normalised ratio (inr). this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. these clots can break off and travel to the lungs (pulmonary embolism).acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up. slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur. blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. heart valve disease can have the same effect, particularly if artificial heart valves have been fitted.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). it is used to stop blood clots forming within the blood vessels
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this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. vitamin k is essential for their production. this is the body's natural way of repairing itself. blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis).acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up. this is usually due to a disturbance in the blood flow within the blood vessels. clotting factors are proteins that are produced by the liver.some people have an increased tendency for blood clots to form within the blood vessels. for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with. heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. these clots can break off and travel to the lungs (pulmonary embolism). your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition. it is used to stop blood clots forming within the blood vessels. without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added. the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. this is known as a thromboembolism.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant. fibrin binds the platelets together, forming a blood clot. the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood. the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k. acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. sometimes, however, a blood clot can form abnormally within the blood vessels. this time is expressed as the international normalised ratio (inr). acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above. clots in the heart can detach and travel to the brain, causing a stroke
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heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. this time is expressed as the international normalised ratio (inr). sometimes, however, a blood clot can form abnormally within the blood vessels. vitamin k is essential for their production. the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. clotting factors are proteins that are produced by the liver. these clots can break off and travel to the lungs (pulmonary embolism). blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. fibrin binds the platelets together, forming a blood clot. clots in the heart can detach and travel to the brain, causing a stroke.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur. for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process.acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up. acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added.some people have an increased tendency for blood clots to form within the blood vessels. your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition. acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above. this is the body's natural way of repairing itself. for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with. the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. it is used to stop blood clots forming within the blood vessels. this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. this is known as a thromboembolism. this is usually due to a disturbance in the blood flow within the blood vessels.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant. the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood. slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis)
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fibrin binds the platelets together, forming a blood clot. this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood. for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added. sometimes, however, a blood clot can form abnormally within the blood vessels.some people have an increased tendency for blood clots to form within the blood vessels. clotting factors are proteins that are produced by the liver. for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant. this is the body's natural way of repairing itself. the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. this is usually due to a disturbance in the blood flow within the blood vessels. acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above. vitamin k is essential for their production. clots in the heart can detach and travel to the brain, causing a stroke. heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. this time is expressed as the international normalised ratio (inr). your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition. acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k.acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up. the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. this is known as a thromboembolism. blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. these clots can break off and travel to the lungs (pulmonary embolism). it is used to stop blood clots forming within the blood vessels. slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart
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for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. these clots can break off and travel to the lungs (pulmonary embolism). a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur. your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant. the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. sometimes, however, a blood clot can form abnormally within the blood vessels.some people have an increased tendency for blood clots to form within the blood vessels. blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with.acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up. it is used to stop blood clots forming within the blood vessels. vitamin k is essential for their production. the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added. clots in the heart can detach and travel to the brain, causing a stroke. heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. this is the body's natural way of repairing itself. acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above. this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. fibrin binds the platelets together, forming a blood clot. this is usually due to a disturbance in the blood flow within the blood vessels. acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k. this time is expressed as the international normalised ratio (inr). clotting factors are proteins that are produced by the liver.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). this is known as a thromboembolism
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acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k. heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition. the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added. clots in the heart can detach and travel to the brain, causing a stroke. acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. this is usually due to a disturbance in the blood flow within the blood vessels. fibrin binds the platelets together, forming a blood clot.some people have an increased tendency for blood clots to form within the blood vessels.acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up. without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur. this is the body's natural way of repairing itself. these clots can break off and travel to the lungs (pulmonary embolism). slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with. this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. vitamin k is essential for their production. clotting factors are proteins that are produced by the liver.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above. for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. this time is expressed as the international normalised ratio (inr). it is used to stop blood clots forming within the blood vessels. this is known as a thromboembolism.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant. sometimes, however, a blood clot can form abnormally within the blood vessels
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for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with. without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur. this time is expressed as the international normalised ratio (inr). acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above. this is the body's natural way of repairing itself. clots in the heart can detach and travel to the brain, causing a stroke.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added.acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up. the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. sometimes, however, a blood clot can form abnormally within the blood vessels. acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k. this is usually due to a disturbance in the blood flow within the blood vessels. clotting factors are proteins that are produced by the liver. these clots can break off and travel to the lungs (pulmonary embolism). this is known as a thromboembolism. slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. fibrin binds the platelets together, forming a blood clot. acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. vitamin k is essential for their production. the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition. the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood.some people have an increased tendency for blood clots to form within the blood vessels. a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. it is used to stop blood clots forming within the blood vessels
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blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. it is used to stop blood clots forming within the blood vessels. a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. clotting factors are proteins that are produced by the liver. sometimes, however, a blood clot can form abnormally within the blood vessels. heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. this time is expressed as the international normalised ratio (inr). this is known as a thromboembolism. vitamin k is essential for their production.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added. these clots can break off and travel to the lungs (pulmonary embolism). this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. fibrin binds the platelets together, forming a blood clot. for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition.some people have an increased tendency for blood clots to form within the blood vessels. this is usually due to a disturbance in the blood flow within the blood vessels.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). clots in the heart can detach and travel to the brain, causing a stroke. this is the body's natural way of repairing itself.acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up. for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with. acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant. slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k. without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur. the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood. the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin
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for example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process.acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up. this is the body's natural way of repairing itself. the activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. the clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood. for this reason, when treating blood clots such as deep vein thrombosis (dvt) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with.nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the uk), which is a type of medicine called an oral anticoagulant. this time is expressed as the international normalised ratio (inr). acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin k.what is it used for?treating and preventing blood clots in the blood vessels, for example in the following cases:preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism). a type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart.some people have an increased tendency for blood clots to form within the blood vessels. fibrin binds the platelets together, forming a blood clot. clots in the heart can detach and travel to the brain, causing a stroke. blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. it is used to stop blood clots forming within the blood vessels. clotting factors are proteins that are produced by the liver. acenocoumarol works by preventing the vitamin k dependent production of the clotting factors described above. slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). sometimes, however, a blood clot can form abnormally within the blood vessels. these clots can break off and travel to the lungs (pulmonary embolism). without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur. the clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. this is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. this is known as a thromboembolism. your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your inr fall into the range that has been shown to be effective at preventing blood clots in your particular condition.the anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added. this is usually due to a disturbance in the blood flow within the blood vessels. vitamin k is essential for their production. acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. heart valve disease can have the same effect, particularly if artificial heart valves have been fitted
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